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Phobia is a 2016 Indian Hindi-language psychological thriller film directed by Chetan Bhagat and co-written by Bhagat, Vikramaditya Motwane, and Abhijat Joshi. It is the sequel to the 2015 film Thappad, which was co-written by Motwane and Bhagat as well.
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The film is directed by Abraham Sher making his directorial debut and the lead role is played by actor Rajkummar Rao.
Description : Phobia is a 2016 Hindi pyschological thriller starring Radhika Apte. Mehak Deo suffers from agoraphobia. She can’t interact with people unknown to her andÂ .Methionine adenosyltransferase 1A isoforms differ in tissue expression, subcellular localisation and activity.
Methionine is an essential sulphur-containing amino acid with significant trophic role and found in all mammals. Synthesis of methionine is regulated by methionine adenosyltransferase (MAT) as its last step. Here we have identified and compared MAT1A and MAT1B, the catalytic subunits of the two isoforms of the enzyme, in rat tissues. The expression of both isoforms in all of the tissues examined indicates that MAT plays an essential role at the high trophic levels. In addition we show that both MAT1A and MAT1B is present both in nuclear and cytosolic fractions. MAT1B is relatively more abundant and present as a complex with the core enzyme MAT2A. In addition, we show that the activity of MAT is significantly higher in liver. Furthermore, using in vitro assay of isolated cytosolic fraction of rat liver we demonstrate that MAT1A and MAT1B are both active and approximately equal in MAT activity. On the basis of these data, we propose that, while different isoenzymes differ in the expression, subcellular localisation and activity, they may in fact have similar functions in different tissues.Remembrance
The internet has been a powerful tool that has allowed us to change lives, create opportunities and take us to new heights. It has given us freedom, access and the ability to communicate more easily and cheaply than any time in the past. We can promote, be part of, work for, and without end … [Read more…]
I’ve always wanted to write a personal horror story, but I never got around to writing it. I was inspired, however, to write a reminiscence at the close of the year. Perhaps, someday, I will write the true story I’ve always wanted to tell, about my childhood experiences as a child of the 80’s. … [Read more…]
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